Neuromodulator injection is the most popular treatment throughout the United States. These injectables are strategically placed to reduce fine lines between the brows, around the eyes, the forehead, and many other areas of the face, jaw and neck. Neuromodulators can also relieve tension and migraine headaches and reduce excessive sweating.

DAXXIFY™ (DaxibotulinumtoxinA-lanm) has been approved by the FDA for injection for the temporary improvement of moderate to severe frown lines (glabellar lines) in adults. DAXXIFY™ is the first and only neuromodulator powered by a cell-penetrating peptide technology (Peptide Exchange Technology™), Revance’s proprietary, synthetic, 35-amino-acid stabilizing excipient with a highly positive charge, and is free of both human serum albumin and animal-based components.

DAXXIFY™ is used cosmetically by injecting a designated facial muscle with a specific number of units to smooth the appearance of fine lines and wrinkles. DAXXIFY™ begins to work in 1-2 days with a full onset at 2 weeks, with its effects lasting 6-9 months. In general, most patients are seeing results that last about twice that of the results they achieved with previously used neuromodulators.